Side Effects of Wegovy: What UAE Patients Should Watch in Dubai UAE ?

Wegovy (semaglutide) injection in Dubai UAE has introduced significant advancements in chronic weight management for patients in Dubai and the UAE. It is highly effective, but like all medications, it comes with a range of potential side effects. Understanding these effects, knowing what to watch out for, and how to manage them is crucial for a successful treatment journey.

It's important to note that side effects can vary from person to person. Some individuals may experience very few, while others might find certain effects more challenging. Fortunately, most side effects, especially the common ones, are typically mild to moderate and tend to improve as the body adjusts to the medication, particularly during the dose escalation phase.

Frequent Side Effects (Most Commonly Reported) These are the side effects that a significant number of Wegovy users in Dubai (and worldwide) experience. They are primarily gastrointestinal in nature, as Wegovy works by slowing digestion and affecting gut hormones.

Nausea: This is the most common side effect, ranging from mild queasiness to a more pronounced feeling of sickness. It often occurs when initiating the medication or increasing the dose.

What to look out for: Persistent or severe nausea that disrupts daily activities or hinders eating.

Tips for managing: Consume smaller, more frequent meals; avoid high-fat, greasy, or very spicy foods; eat slowly and stop when full; stay hydrated; avoid lying down immediately after eating. Your doctor may recommend anti-nausea medication.

Diarrhea: Loose or frequent bowel movements.

What to watch for: Severe diarrhea leading to dehydration (e.g., dry mouth, decreased urination, dizziness).

Management tips: Stay hydrated with water and electrolyte-rich fluids; avoid trigger foods; consider a bland diet temporarily. Over-the-counter anti-diarrheal medication may be recommended by your doctor if needed.

Constipation: Infrequent or difficult bowel movements.

What to watch for: Severe abdominal pain, inability to pass gas or stool, or persistent constipation.

Management tips: Increase fiber intake from fruits, vegetables, and whole grains; drink plenty of water; engage in regular physical activity. Over-the-counter laxatives (e.g., fiber supplements, stool softeners) can be discussed with your doctor or pharmacist.

Vomiting: Expelling stomach contents.

What to watch for: Frequent or severe vomiting, especially if accompanied by signs of dehydration.

Management tips: Similar to nausea – small, bland meals, hydration, and avoiding trigger foods. Seek medical advice if vomiting is persistent.

Stomach (Abdominal) Pain: Discomfort or cramping in the belly area.

What to watch for: Severe or persistent abdominal pain, especially if it radiates to your back (could indicate pancreatitis – see serious side effects).

Management tips: Dietary adjustments often help. Report any severe or worsening pain to your doctor immediately.

Headache:

Management tips: Over-the-counter pain relievers, adequate hydration, and rest. If headaches persist or worsen, consult your doctor.

Fatigue (Tiredness):

Management tips: Ensure sufficient sleep, maintain a balanced diet, and stay hydrated. Fatigue often improves over time.

Other commonly reported side effects include dyspepsia (indigestion/upset stomach), dizziness, abdominal distension (bloating), belching, gas (flatulence), gastroenteritis (stomach flu), heartburn, and runny nose/sore throat.

Serious Side Effects (Less Common but Require Immediate Attention) While rare, some serious side effects can occur. Patients in the UAE should be aware of these and seek immediate medical attention if they experience any symptoms.

Pancreatitis (Inflammation of the Pancreas):

What to watch for: Severe, persistent stomach pain that may radiate to your back, with or without vomiting.

Action: Discontinue Wegovy immediately and contact your healthcare provider or seek emergency medical help.

Gallbladder Problems (Gallstones or Inflammation):

What to watch for: Severe upper stomach (abdominal) pain, fever, yellowing of the skin or eyes (jaundice), or clay-colored stools.

Action: Contact your healthcare provider immediately.

Acute Kidney Injury (Kidney Problems):

What to watch for: Reduced urination, swelling in your legs or feet, nausea, vomiting, or unusual fatigue. Severe diarrhea and vomiting can lead to dehydration, worsening kidney problems.

Action: Stay well-hydrated, and if symptoms arise, contact your doctor.

Serious Allergic Reactions:

What to watch for: Swelling of your face, lips, tongue, or throat; difficulty breathing or swallowing; severe rash or itching; fainting or dizziness; or a rapid heartbeat.

Action: Seek emergency medical help immediately (call 999 or go to the nearest emergency room).

Increased Heart Rate:

What to watch for: Sensation of your heart racing or pounding in your chest for several minutes.

Action: Inform your healthcare provider.

Thyroid